William Karnes, MD
NPI 1881652998 · Gastroenterology Physician · Orange, CA
Enrolled with Medicare as Practitioner - Internal Medicine · source: CMS PECOS Public Provider Enrollment (2026.04.01)
William Karnes, MD is a Gastroenterology Physician provider in Orange, CA (NPI 1881652998).
Provider details
- NPI number
- 1881652998
- Entity type
- Individual
- Primary specialty
- Gastroenterology PhysicianAllopathic & Osteopathic Physicians
- Credential
- MD
- Sex
- Male
- Sole proprietor
- Yes
- License
- G57458 (CA)
Specialties & taxonomies
Allopathic & Osteopathic Physicians
Profile Score
A profile completeness & documented-activity index — NOT a quality, outcomes, or patient-satisfaction rating.
- Registry tenure28% of score
20 yrs in NPPES registry
- Profile completeness28% of score
100% of core fields populated
- Practice footprint17% of score
1 documented practice location
- Medicare service volume (vs. specialty peers)28% of score
827 Medicare services, 2024 (ranked within specialty)
Medicare volume is ranked against active providers in the same specialty. Signals a provider has no public data for (e.g. Medicare claims) are left out of the score entirely — never counted as zero — so providers without that data are not penalized. See the full formula and weights in our methodology.
What this provider does (Medicare)
Based on Medicare fee-for-service claims, 2024; not all care is captured.
| Service (HCPCS) | Medicare services | Typical Medicare-allowed (2024) |
|---|---|---|
| Removal of Polyps Or Growths of Large Bowel Using an Endoscope With Mechanical Snare45385 | 142 | $261 |
| Biopsy of Esophagus, Stomach, And/Or Upper Small Bowel Using a Flexible Endoscope43239 | 101 | $103 |
| Established Patient Office Or Other Outpatient Visit With Moderate Level of Decision Making, If Using Time, 30 Minutes Or More99214 | 97 | $145 |
| Biopsy of Large Bowel Using a Flexible Endoscope45380 | 78 | $112 |
| New Patient Office Or Other Outpatient Visit With Moderate Level of Medical Decision Making, If Using Time, 45 Minutes Or More99204 | 56 | $189 |
What this provider prescribes (Medicare Part D)
Top drugs by Medicare Part D claim volume, 2024 · 19 distinct drugs on file.
| Drug | Part D claims (2024) | Beneficiaries |
|---|---|---|
| Sodium Chloride/Nahco3/Kcl/Pegbrand: Peg 3350-Electrolyte | 309 | 277 |
| Omeprazole | 243 | 100 |
| Pantoprazole Sodium | 133 | 44 |
| Famotidine | 131 | 41 |
| Linaclotidebrand: Linzess | 77 | 26 |
| Sucralfate | 32 | 16 |
| Lipase/Protease/Amylasebrand: Creon | 29 | — |
Practice location
Mailing address
Registry dates
- Enumerated
- 2006-05-01
- Last updated
- 2014-09-08
Frequently asked questions
- What is William Karnes's NPI number?
- William Karnes's National Provider Identifier (NPI) is 1881652998, a unique 10-digit ID issued by CMS for use in standard healthcare transactions.
- What is William Karnes's specialty?
- William Karnes is listed in the NPPES registry with a primary specialty of Gastroenterology Physician (Allopathic & Osteopathic Physicians).
- Where is William Karnes located?
- William Karnes's practice location on file with NPPES is 101 the City Dr S Bldg 22c, Orange, CA 92868-3201.
- What is William Karnes's phone number?
- The practice phone number listed in the NPPES registry for William Karnes is (888) 717-4463.
- Does William Karnes accept Medicare?
- William Karnes is approved to bill Medicare according to CMS PECOS enrollment data (2026.04.01). Confirm current participation with the provider before scheduling.
- Is William Karnes's NPI active?
- Yes — William Karnes's NPI (1881652998) is active in the NPPES registry as of the last update on 2014-09-08.
Source: CMS NPPES Data Dissemination (June 2026). NPI Central is not affiliated with CMS. Data is provided as-is from the public registry.