Mark Ayers, MD
NPI 1669658753 · Internal Medicine Physician · Seneca, SC
Enrolled with Medicare as Order and Referring Only - Internal Medicine · source: CMS PECOS Public Provider Enrollment (2026.04.01)
Mark Ayers, MD is a Internal Medicine Physician provider in Seneca, SC (NPI 1669658753).
Provider details
- NPI number
- 1669658753
- Entity type
- Individual
- Primary specialty
- Internal Medicine PhysicianAllopathic & Osteopathic Physicians
- Credential
- MD
- Sex
- Male
- Sole proprietor
- No
- License
- TL25652 (SC)
Specialties & taxonomies
Allopathic & Osteopathic Physicians
Profile Score
A profile completeness & documented-activity index — NOT a quality, outcomes, or patient-satisfaction rating.
- Registry tenure33% of score
18 yrs in NPPES registry
- Profile completeness33% of score
100% of core fields populated
- Practice footprint20% of score
1 documented practice location
- Open Payments transparency13% of score
Has Open Payments disclosures (2024)
Signals a provider has no public data for (e.g. Medicare claims) are left out of the score entirely — never counted as zero — so providers without that data are not penalized. See the full formula and weights in our methodology.
What this provider prescribes (Medicare Part D)
Top drugs by Medicare Part D claim volume, 2024 · 64 distinct drugs on file.
| Drug | Part D claims (2024) |
|---|---|
| Quetiapine Fumarate | 103 |
| Levothyroxine Sodium | 98 |
| Metformin Hcl | 79 |
| Omeprazole | 75 |
| Clonazepam | 68 |
| Lacosamide | 67 |
| Atorvastatin Calcium | 62 |
| Fluticasone Propionate | 56 |
| Carbamazepine | 54 |
Transparency — industry payments
Based on CMS Open Payments, 2024; not all care is captured.
$405 across 16 records (Open Payments 2024)
Open Payments discloses payments and transfers of value (meals, travel, consulting, research, royalties) from drug and device makers to providers. This is a transparency signal, not a verdict — such payments are legal and common, and their presence is neither an endorsement nor a criticism. Source: CMS Open Payments, program year 2024.
Practice location
Mailing address
Registry dates
- Enumerated
- 2008-01-18
- Last updated
- 2009-03-17
Frequently asked questions
- What is Mark Ayers's NPI number?
- Mark Ayers's National Provider Identifier (NPI) is 1669658753, a unique 10-digit ID issued by CMS for use in standard healthcare transactions.
- What is Mark Ayers's specialty?
- Mark Ayers is listed in the NPPES registry with a primary specialty of Internal Medicine Physician (Allopathic & Osteopathic Physicians).
- Where is Mark Ayers located?
- Mark Ayers's practice location on file with NPPES is 298 Memorial Dr, Seneca, SC 29672-9443.
- What is Mark Ayers's phone number?
- The practice phone number listed in the NPPES registry for Mark Ayers is (843) 237-3378.
- Does Mark Ayers accept Medicare?
- Mark Ayers is approved to bill Medicare according to CMS PECOS enrollment data (2026.04.01). Confirm current participation with the provider before scheduling.
- Is Mark Ayers's NPI active?
- Yes — Mark Ayers's NPI (1669658753) is active in the NPPES registry as of the last update on 2009-03-17.
Source: CMS NPPES Data Dissemination (June 2026). NPI Central is not affiliated with CMS. Data is provided as-is from the public registry.