Melissa Knowles, CRNA
NPI 1518495910 · Certified Registered Nurse Anesthetist · Charleston, SC
Enrolled with Medicare as Practitioner - Certified Registered Nurse Anesthetist (crna) · source: CMS PECOS Public Provider Enrollment (2026.04.01)
Melissa Knowles, CRNA is a Certified Registered Nurse Anesthetist provider in Charleston, SC (NPI 1518495910).
Provider details
- NPI number
- 1518495910
- Entity type
- Individual
- Primary specialty
- Certified Registered Nurse AnesthetistPhysician Assistants & Advanced Practice Nursing Providers
- Credential
- CRNA
- Sex
- Female
- Sole proprietor
- No
- License
- 27957 (SC)
Specialties & taxonomies
Physician Assistants & Advanced Practice Nursing Providers
Physician Assistants & Advanced Practice Nursing Providers
Profile Score
A profile completeness & documented-activity index — NOT a quality, outcomes, or patient-satisfaction rating.
- Registry tenure28% of score
9 yrs in NPPES registry
- Profile completeness28% of score
100% of core fields populated
- Practice footprint17% of score
1 documented practice location
- Medicare service volume (vs. specialty peers)28% of score
69 Medicare services, 2024 (ranked within specialty)
Medicare volume is ranked against active providers in the same specialty. Signals a provider has no public data for (e.g. Medicare claims) are left out of the score entirely — never counted as zero — so providers without that data are not penalized. See the full formula and weights in our methodology.
What this provider does (Medicare)
Based on Medicare fee-for-service claims, 2024; not all care is captured.
| Service (HCPCS) | Medicare services | Typical Medicare-allowed (2024) |
|---|---|---|
| Anesthesia for Other Procedure on Esophagus, Stomach, Or Upper Small Bowel Using an Endoscope00731 | 33 | $66 |
| Anesthesia for Other Procedure on Large Bowel Using an Endoscope00811 | 24 | $60 |
| Anesthesia for X-Ray Or Radiation Therapy01922 | 12 | $84 |
Typical Medicare-allowed amounts for these services range $60–$84 (2024). The Medicare-allowed amount is what Medicare recognizes for a service under fee-for-service — a reference figure for 2024, not a price quote and not what you would be billed. Medicare Part B covers roughly an eighth of all NPIs (65+ skew); services with fewer than 11 beneficiaries are suppressed by CMS. Source: CMS Medicare Physician & Other Practitioners, by Provider & Service.
Practice location
Mailing address
Registry dates
- Enumerated
- 2017-05-30
- Last updated
- 2026-02-05
- Certified
- 2026-02-05
Frequently asked questions
- What is Melissa Knowles's NPI number?
- Melissa Knowles's National Provider Identifier (NPI) is 1518495910, a unique 10-digit ID issued by CMS for use in standard healthcare transactions.
- What is Melissa Knowles's specialty?
- Melissa Knowles is listed in the NPPES registry with a primary specialty of Certified Registered Nurse Anesthetist (Physician Assistants & Advanced Practice Nursing Providers).
- Where is Melissa Knowles located?
- Melissa Knowles's practice location on file with NPPES is 2095 Henry Tecklenburg Dr, Charleston, SC 29414-5733.
- What is Melissa Knowles's phone number?
- The practice phone number listed in the NPPES registry for Melissa Knowles is (843) 402-1436.
- Does Melissa Knowles accept Medicare?
- Melissa Knowles is approved to bill Medicare according to CMS PECOS enrollment data (2026.04.01). Confirm current participation with the provider before scheduling.
- Is Melissa Knowles's NPI active?
- Yes — Melissa Knowles's NPI (1518495910) is active in the NPPES registry as of the last update on 2026-02-05.
Source: CMS NPPES Data Dissemination (June 2026). NPI Central is not affiliated with CMS. Data is provided as-is from the public registry.