What is Rylee Cook's NPI number?

Rylee Cook's National Provider Identifier (NPI) is 1235973116, a unique 10-digit ID issued by CMS for use in standard healthcare transactions.

What is Rylee Cook's specialty?

Rylee Cook is listed in the NPPES registry with a primary specialty of Internal Medicine Physician (Allopathic & Osteopathic Physicians).

Where is Rylee Cook located?

Rylee Cook's practice location on file with NPPES is 101 E. Wood St., Spartanburg, SC 29303.

What is Rylee Cook's phone number?

The practice phone number listed in the NPPES registry for Rylee Cook is (864) 560-6285.

Does Rylee Cook accept Medicare?

Rylee Cook is approved to bill Medicare according to CMS PECOS enrollment data (2026.04.01). Confirm current participation with the provider before scheduling.

Is Rylee Cook's NPI active?

Yes — Rylee Cook's NPI (1235973116) is active in the NPPES registry as of the last update on 2025-06-05.

IndividualActiveAccepts Medicare

Rylee Cook, MD

NPI 1235973116 · Internal Medicine Physician · Spartanburg, SC

Enrolled with Medicare as Order and Referring Only - Internal Medicine · source: CMS PECOS Public Provider Enrollment (2026.04.01)

Rylee Cook, MD is a Internal Medicine Physician provider in Spartanburg, SC (NPI 1235973116).

Provider details

NPI number: 1235973116
Entity type: Individual
Primary specialty: Internal Medicine PhysicianAllopathic & Osteopathic Physicians
Credential: MD
Sex: Female
Sole proprietor: No
License: LL92540 (SC)

Specialties & taxonomies

Internal Medicine PhysicianPrimary207R00000XLicense LL92540 (SC)
Allopathic & Osteopathic Physicians

Profile Score

Established profile(62/100 index)

A profile completeness & documented-activity index — NOT a quality, outcomes, or patient-satisfaction rating.

Registry tenure33% of score
1 yr in NPPES registry
Profile completeness33% of score
100% of core fields populated
Practice footprint20% of score
1 documented practice location
Open Payments transparency13% of score
Has Open Payments disclosures (2024)

Signals a provider has no public data for (e.g. Medicare claims) are left out of the score entirely — never counted as zero — so providers without that data are not penalized. See the full formula and weights in our methodology.

Transparency — industry payments

Based on CMS Open Payments, 2024; not all care is captured.

$23 across 1 record (Open Payments 2024)

Open Payments discloses payments and transfers of value (meals, travel, consulting, research, royalties) from drug and device makers to providers. This is a transparency signal, not a verdict — such payments are legal and common, and their presence is neither an endorsement nor a criticism. Source: CMS Open Payments, program year 2024.

Practice location

101 E. Wood St.

Spartanburg, SC 29303

Phone: (864) 560-6285

Street-level locationGet directions

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Mailing address